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Deborah M. Kristan, Ph.D.

Deborah M. Kristan, Ph.D.

Deborah M. Kristan, Ph.D. profile picture
Professor Biological Sciences

About Deborah M. Kristan, Ph.D.

Prior to Dr. Kristan’s appointment at CSUSM in Fall 2003, she was a postdoctoral fellow in the Department of Biological Sciences at the University of Idaho.  Research interests include physiological ecology (especially the effects on chronic parasite infection on ability of small rodents to respond to other environmental demands such as cold exposure, lactation, and caloric restriction), biology of aging, and effects of domestication on morphology and physiology.

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University of California, Riverside.

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Gomez, S.R., Morgans, S. and Kristan, D.M. 2019. Rapamycin exposure to host and to adult worms affects life history traits of Heligmosomoides bakeri. Exp. Parasitol. 204, 107720.

Rodriguez, K.A., Valentine, J.M., Kramer, D.A., Gelfond, J.A., Kristan, D.M., Nevo, E., and Buffenstein, R. 2016. Determinants of rodent longevity in the chaperone-protein degradation network. Cell Stress Chaperones 21:453-466.

Lewis, K.N., Watson, E., Edrey, Y., Kristan, D.M., Nevo, E. and Buffenstein, R. 2015. Regulation of Nrf2-signaling and longevity in naturally long-lived rodents. Proc. Natl. Acad. Sci. 112:3722-3727.

Clark, P.R., Ward, T.W., Lang, S.A., Saghbini, A., Kristan, D.M. 2013. Order of inoculation during Heligmosomoides bakeri and Hymenolepis microstoma coinfection alters parasite life history and host responses. Pathogens 2:130-152.

Edrey, Y.H., Casper, D. Huchon, D., Mele, J., Gelfond, J.A., Kristan, D.M., Nevo, E., Buffenstein, R.B. 2012. Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity. Aging Cell 11:213-222.

Kristan, D.M. 2008. Calorie restriction and susceptibility to intact pathogens. AGE 30:147-156.

Holmes, D.K. and Kristan, D.M. 2008. Comparative and alternative approaches and novel animal models for aging research. AGE 30:63-73.

Kristan, D.M. 2007. Chronic Calorie Restriction Increases Susceptibility of Laboratory Mice (Mus musculus) to a Primary Intestinal Parasite Infection. Aging Cell 6:817-825.

Kristan, D.M. and K.A. Hammond.  2006. Effects of three simultaneous demands on glucose transport, resting metabolism and morphology of laboratory mice.  J. Comp. Physiol. B. 176:139-151.

Shupe, J.M., Kristan, D.M. Austad, S.N. Stenkamp, D.L. 2006.  The eye of the laboratory mouse remains anatomically adapted for natural conditions.  Brain Behav. Evol.67:39-52.

Kristan, D.M. and K.A. Hammond. 2004. Aerobic performance of wild-derived house mice does not change with cold exposure or intestinal parasite infection.  Physiol. Biochem. Zool. 77(3): 440-449.

Kristan, D.M. and K.A. Hammond. 2004. Morphological plasticity varies with duration of infection: evidence from lactating and virgin wild-derived house mice (Mus musculus) infected with an intestinal parasite (Heligmosomoides polygyrus: Nematoda).  J. Exp. Biol 207: 2351-2360.

Kristan, D.M. 2004. Intestinal nematode infection affects host life history and offspring susceptibility to parasitism. J. Anim. Ecol. 73: 227-238.

Kristan, D.M. and K.A. Hammond.  2003. Physiological and morphological responses to simultaneous cold exposure and parasite infection by wild-derived house mice.  Func. Ecol. 17: 464-471.

Austad, S.N. and D.M. Kristan.  2003. Are mice calorically restricted in nature?   Aging Cell 2: 201-207.

Kristan, D.M. 2002. Effects of intestinal nematodes during lactation: consequences for host morphology, physiology and offspring mass.  J. Exp. Biol. 205: 3955-3965.

Kristan, D.M. 2002. Maternal and direct effects of the intestinal nematode Heligmosomoides polygyrus on offspring growth and susceptibility to infection.  J. Exp. Biol. 205: 3967-3977.

Hammond, K.A., M.A. Chappell, and D. M. Kristan.  2002. Developmental plasticity in aerobic performance in deer mice (Peromyscus maniculatus). Comp. Biochem. Physiol. A 133:213-224

Kristan, D.M. and K.A. Hammond.  2001. Parasite infection and caloric restriction induce physiological and morphological plasticity. Am. J. Physiol. 281: R502-R510.

Hammond, K.A. and D.M. Kristan.  2000.  Responses to lactation and cold exposure by deer mice (Peromyscus maniculatus).  Physiol. Biochem. Zool. 73:547-556.

Kristan, D.M. and K.A. Hammond.  2000.  Combined effects of cold exposure and sub-lethal intestinal parasites on host morphology and physiology.  J. Exp. Biol. 203:3495-3504.

Zuk, M., T. Kim, D.M. Kristan, and L.T. Luong. 1997. Sex, pain and parasites.  Parasitol. Today. 13:332-333.

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