Dr. Iafe graduated cum laude with Honors from Loyola Marymount University in Los Angeles, where he carried out research with Dr. James Roe and Dr. James Landry. He completed his masters work in Computational Chemistry with Dr. Kendall N. Houk and earned a PhD in Chemistry with Dr. Craig Merlic at UCLA. Following his graduate work, he completed a three-year appointment as a Visiting Assistant Professor at the W.M. Keck Science Department at the Claremont Colleges and postdoctoral work with Prof. Anna Wenzel. In 2014, Dr. Iafe joined the Department of Chemistry & Biochemistry at CSUSM, and received tenure and promotion to Associate Professor in 2020. Dr. Iafe’s research interest include method development and small molecule synthesis in organic chemistry, and at CSUSM he teaches classes in organic chemistry (CHEM 200, CHEM 201, Chem 201L, Chem 202, Chem 202L, Chem 502).
Publications (* denotes undergraduate student)
- *King, B. H.; *Wang, M. L.; *Jesse, K. A.; *Kaur, G.; *Tran, B.; *Walser-Kuntz, R.; Iafe, R. G.; Wenzel, A. G. "Silver-Catalyzed, N-Formylation of Amines Using Glycol Ethers." J. Org. Chem. 2020, 85, 13256–13263.
- *Oakley, J. V.; *Stanley, T. J.; *Jesse, K. A.; *Melanese, A. K; *Alvarez, A. A.; Prince, A. L.; Cain, S. E.; Wenzel, A. G.; Iafe, R. G. "Gold-Catalyzed Friedel–Crafts-like Reaction of Benzylic Alcohols to Afford 1,1-Diarylalkanes." Euro. J. Org. Chem. 2019, 42, 7063–7066.
- Karabiyikoglu, S.; Iafe, R. G.; Merlic, C. A. "Ring-Closing Metathesis with Vicinal Dibromoalkenes as Protected Alkynes: A Synthetic Approach to Macrocyclic Enynes." Org. Lett. 2015, 17, 5248–5251.
- *Vinson, A. R. S.; *Davis, V. K.; *Arunasalam, A.; *Jesse, K. A.; *Hamilton, R. E.; *Shattuck, M. A.; *Hu, A. C.; Iafe, R. G.; Wenzel, A. G. "Gold-Catalyzed, SN1-Type Reaction of Alcohols to Ethers and Cbz-Protected Amines." Synlett 2015, 26, 765–770.
- Iafe, R. G.; *Kuo, J. L.; Hochstatter, D. G.; *Saga, T.; *Turner, J. W.; Merlic, C. A. "Increasing the Efficiency of the Transannular Diels-Alder Strategy via Palladium(II)-Catalyzed Macrocyclizations." Org. Lett. 2013, 15, 582–585.
- Iafe, R. G.; Chan, D. G.; *Kuo, J. L.; Boon, B. A.; *Faizi, D. J.; Saga, T.; *Turner, J. W.; Merlic, C. A. "Cyclization Strategies to Polyenes Using Pd(II)-Catalyzed Couplings of Pinacol Vinylboronates." Org. Lett. 2012, 14, 4282–4285.
- Gutierrez, O.; Iafe, R. G.; Houk, K. N. "Origin of Stereoselectivity in the Imidazolidinone-Catalyzed Reductions of Cyclic α,β-Unsaturated Ketones." Org. Lett. 2009, 11, 4298–4301.
- Ess, D. H.; Wheeler, S. E.; Iafe, R. G.; Xu, L.; Celebi-Olcum, N.; Houk, K. N. "Bifurcations on Potential Energy Surfaces of Organic Reactions." Angew. Chem. Int. Ed. 2008, 47, 7592–7601.
- Iafe, R. G.; Houk, K. N. "Intramolecular Hetero-Diels-Alder Reactions of Imine and Iminium Dienophiles: Quantum Mechanical Exploration of Mechanisms and Stereoselectivities." J. Org. Chem. 2008, 73, 2679–2686.
- Iafe, R. G.; Houk, K. N. "Stereoselectivity Control by Torsional Steering in an Intramolecular Diels-Alder Reaction of Vinyl Oxocarbenium Ions." Org. Lett. 2006, 8, 3469–3472.
Grants/Fellowships
- 2023: Green Chemistry Education Challenge Award $10,000
- 2023: CALM $4,000
- 2023: CSUPERB CD $15,000
- 2023: Pfizer AIR Diversity (Llamas) $20,000
- 2020: NSF S-STEM $999,875
- 2020: CSUPERB PCS (Stockton) $8,000
- 2019: Hamilton $1,000
- 2019: CSUPERB PCS (Shoemaker) $8,000
- 2019: ACS DOC SURF (Melanese) $5,000
- 2018: FC PD Grant $800
- 2018: OGSR GPSM $1,732
- 2018: NCHEA *NSPIRE Graduate Student Lecture Series $3,000
- 2018: Jean Dreyfus Lectureship for Undergraduate Institutions $18,500
- 2018: OGSR GPSM $3,000
- 2017: CALM $1,000
- 2017: CSUPERB PCS (Apolinar) $8,000
- 2015. OGSR GPSM $3,000
- 2015. CSUPERB NI $15,000
- CHEM 200: Bridge to Organic Chemistry
- CHEM 201: Organic Chemistry I
- CHEM 201L: Organic Chemistry I Lab
- CHEM 202: Organic Chemsitry II
- CHEM 202L: Organic Chemistry II Lab
- Chem 399: Special Problems in Chemistry - Laboratory
- CHEM 499: Senior Laboratory Thesis and Seminar
- CHEM 502: Advanced Organic Synthesis
- CHEM 691: Graduate Student Colloquium in Chemistry and Biochemistry
- CHEM 697: Directed Studies
- CHEM 698: Thesis Research
*To enroll in CHEM 399/CHEM 499, you must go through the Department's application process. CHEM 697/CHEM 698 is restricted to Chemistry MS students. Prospective undergraduate and M.S. researchers are encouraged to contact Prof. Iafe at riafe(at)csusm.edu. Prospective M.S. students should apply to the graduate program at CSUSM. Individuals seeking to join the Iafe lab should expect to undergo a rigorous selection process that includes submission of relevant application materials and an in-person interview.
Awards
- 2021-2022 ACS Outstanding Student Club Award
- 2020-2021 ACS Commendable and Green Chemistry Student Club Award
- 2019-2020 ACS Outstanding Student Club Award
- 2019 Student Organization of the Year Tukwut Leadership Award
- 2018-2019 ACS Commendable Student Club Award
- 2017-2018 ACS Honorable Mention Student Club Award
Links: Instagram, Twitter, Tukwut Trax
Graduate Students
Kasumi Faile
Chemistry MS Option
Undergraduate Students
Sebastian Aguero
Goldwater Scholar, CBTLC Scholar
Major: Chemistry
Plans after graduation: complete a Ph.D. program in chemistry.
Karissa Grier
Fenstermaker Summer Scholar
Major: Chemistry, Minor: Biology
In my free time I enjoy competitive powerlifting and spending time with my family.
Diana Llamas
Pfizer AIR Diversity Research Fellow
Major: Biochemistry
After graduation I plan on getting a Ph.D. in organic chemistry, once I earn my Ph.D. I will then pursue a career as a researcher in the pharmaceutical industry. Some of my hobbies include drawing and hanging out with my bird named Pablo.
Arianna Serrano
Bridges Scholar
Major: Chemistry
I am a Palomar and MiraCosta college student. After undergraduate school, I plan to go to graduate school to get a Ph.D. In chemistry to work in the field of pharmaceutical research. My hobbies include hiking, photography, and traveling.
Group Photos:
Thank you to the following for providing financial assistance to our lab: CSUSM, NSF, Beckman Foundation, Dreyfus Foundation, Goldwater, Pfizer, Hologic, ACS Division of Organic Chemistry, Genentech, McNair, CTREE, U-Rise, NCHEA, CSUSM OGSR, Hamilton, San Diego Foundation, and CSUPERB.